From IMDB:

Weeds stars Mary-Louise Parker and Jeffrey Dean Morgan have sparked rumors they have rekindled their relationship - after they attended the premiere of P.S. I Love You together. The pair, who play husband and wife on the hit show, split after six months together in June. But Parker and Morgan were spotted at the movie premiere in Hollywood on Sunday with their arms around one another and holding hands. When asked by People magazine what he thought of his date, Grey’s Anatomy star Morgan responded, “What about her?” before raising his eyebrow and grinning.